Living with psoriasis can feel like being stuck in an endless cycle of flare-ups, creams and questions. Psoriasis is a long-term condition, but with the right treatment plan it can be managed effectively. With modern therapies, many patients achieve good control of their symptoms and live comfortably. If you have been recently diagnosed, or if your current treatment is no longer working, it helps to understand the different options available in Singapore and how each one helps.
Topical medications are often the first step in treatment. These include creams such as calcipotriol or combination formulations like calcipotriol with betamethasone dipropionate. These help reduce scaling and inflammation on affected skin. These topicals are effective for smaller or localised patches. They are often prescribed as a first-line treatment and may also be used alongside other therapies.
When creams alone are not enough, your dermatologist may recommend phototherapy. This treatment uses controlled doses of narrow-band ultraviolet B (UVB) light to:
It is delivered in a clinical setting under specialist supervision to ensure safety and effectiveness. Phototherapy is especially useful as an adjunctive treatment for patients with moderate psoriasis and is available at our clinic.
For patients with more extensive or resistant psoriasis, oral medications may be prescribed. These treatments act throughout the body to regulate the immune system and reduce inflammation.
Common systemic treatments offered at our clinic include:
These drugs can be highly effective, but their use must be carefully balanced with possible side effects, so regular monitoring is required.
A newer oral option is Apremilast, a PDE4 inhibitor that belongs to a more selective class of immunosuppressant agents. It works by targeting specific pathways in the immune system to reduce inflammation. This therapy offers a convenient alternative for patients who may not respond well to or tolerate traditional systemic drugs. Apremilast is generally well tolerated, though it still requires medical supervision and follow-up.
Biologics are advanced medications that have changed how psoriasis is treated. Unlike older drugs that broadly suppress the immune system, biologics target specific proteins (such as TNF-alpha, IL-17, or IL-23) that drive inflammation and rapid skin cell growth.
They are given by injection, usually once every few weeks. For many patients, biologics provide:
Since biologics affect the immune system, patients are carefully evaluated for suitability, taking into account their medical history, existing health conditions and lifestyle factors. They are usually prescribed for moderate to severe psoriasis or when other treatments have not been effective.
Medical treatment works best when paired with healthy habits. You can reduce flare-ups and improve results by:
Psoriasis is a complex condition that can look and behave differently from one patient to another. The most effective care comes from a dermatologist who can evaluate your skin, recommend suitable therapies and tailor treatment to your health and lifestyle.
At our psoriasis clinic in Orchard, we offer a full range of evidence-based treatments, from topical therapies to phototherapy and advanced oral medications like Apremilast. With specialist care, psoriasis can be managed effectively, giving you clearer skin and greater confidence.
While psoriasis cannot be cured, it can be controlled. From mainstay treatments such as topical creams and phototherapy to newer options like Apremilast and biologic therapies, effective treatments are available at our clinic.
If you are looking for a psoriasis specialist, send us an enquiry or call us at +6567341411 to explore your options and start a personalised treatment plan.

| Main Line | : (65) 6734 1411 |
| Fax | : (65) 6235 5900 |
| Mon - Fri | : 8:30am - 5:00pm |
| Sat | : 8:00am - 1:00pm |
| Closed on Sundays and Public Holidays | |